Cargando…

IGF2BP2 Regulates MALAT1 by Serving as an N6-Methyladenosine Reader to Promote NSCLC Proliferation

Insulin-like growth factor 2 (IGF2) mRNA-binding protein 2 (IGF2BP2) is an important posttranscriptional regulatory for stability and m6A modification. Here, we investigated the role of IGF2BP2 in non–small-cell lung cancer (NSCLC) proliferation. TCGA database was used to predict the expression and...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Le, Lei, Guangyan, Chen, Zhenghong, Zhang, Yili, Huang, Chen, Chen, Wenjuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802805/ https://www.ncbi.nlm.nih.gov/pubmed/35111811 http://dx.doi.org/10.3389/fmolb.2021.780089

Ejemplares similares

IGF2BP2 regulates DANCR by serving as an N6-methyladenosine reader
por: Hu, Xiaoge, et al.
Publicado: (2019)

Clinical Significance of an m6A Reader Gene, IGF2BP2, in Head and Neck Squamous Cell Carcinoma
por: Deng, Xiaoli, et al.
Publicado: (2020)

IGF2BP1, a Conserved Regulator of RNA Turnover in Cancer
por: Glaß, Markus, et al.
Publicado: (2021)

Systematic Analyses of the Role of the Reader Protein of N(6)-Methyladenosine RNA Methylation, YTH Domain Family 2, in Liver Hepatocellular Carcinoma
por: Shao, Xiang-yang, et al.
Publicado: (2020)

RNA N6-methyladenosine reader IGF2BP3 interacts with MYCN and facilitates neuroblastoma cell proliferation
por: Zhu, Kai, et al.
Publicado: (2023)

N(6)-methyladenosine reader IGF2BP3 as a prognostic Biomarker contribute to malignant progression of glioma
por: Zheng, Xin, et al.
Publicado: (2023)

MYC-activated RNA N6-methyladenosine reader IGF2BP3 promotes cell proliferation and metastasis in nasopharyngeal carcinoma
por: Du, Mingyu, et al.
Publicado: (2022)

Multi-omics analysis of N6-methyladenosine reader IGF2BP3 as a promising biomarker in pan-cancer
por: Chen, Pin, et al.
Publicado: (2023)

MicroRNA 101 Attenuated NSCLC Proliferation through IDH2/HIFα Axis Suppression in the Warburg Effect
por: Han, Le, et al.
Publicado: (2022)

RNA N6-methyladenosine reader IGF2BP3 regulates cell cycle and angiogenesis in colon cancer
por: Yang, Zhou, et al.
Publicado: (2020)

Mechanistic studies of MALAT1 in respiratory diseases
por: Wu, Wenzheng, et al.
Publicado: (2022)

N6-Methyladenosine Methylation Regulator RBM15 is a Potential Prognostic Biomarker and Promotes Cell Proliferation in Pancreatic Adenocarcinoma
por: Zhao, Zhiying, et al.
Publicado: (2022)

N(6)-Methyladenosine, DNA Repair, and Genome Stability
por: Qu, Fei, et al.
Publicado: (2021)

CXCR2 May Serve as a Useful Index of Disease Activity in Interstitial Lung Disease Associated With Primary Sjögren’s Syndrome
por: Zhu, Xiaofang, et al.
Publicado: (2021)

N(6)-methyladenosine (m(6)A) reader IGF2BP2 promotes gastric cancer progression via targeting SIRT1
por: Zhang, Zili, et al.
Publicado: (2022)

Downregulation of CacyBP by CRISPR/dCas9-KRAB Prevents Bladder Cancer Progression
por: Zheng, Hanxiong, et al.
Publicado: (2021)

New Insights on the Role of N(6)-Methyladenosine RNA Methylation in the Physiology and Pathology of the Nervous System
por: Dermentzaki, Georgia, et al.
Publicado: (2020)

Alteration of N6-Methyladenosine RNA Profiles in Cisplatin-Induced Acute Kidney Injury in Mice
por: Li, Can-Ming, et al.
Publicado: (2021)

TMPRSS2 Serves as a Prognostic Biomarker and Correlated With Immune Infiltrates in Breast Invasive Cancer and Lung Adenocarcinoma
por: Xiao, Xinhua, et al.
Publicado: (2022)

Biochemical characterization and identification of ferulenol and embelin as potent inhibitors of malate:quinone oxidoreductase from Campylobacter jejuni
por: Kabongo, Augustin Tshibaka, et al.
Publicado: (2023)

N(6)-methyladenosine (m(6)A) reader IGF2BP1 facilitates clear-cell renal cell carcinoma aerobic glycolysis
por: Yuan, Bao, et al.
Publicado: (2023)

RNA N6-methyladenosine reader IGF2BP3 promotes acute myeloid leukemia progression by controlling stabilization of EPOR mRNA
por: Fan, Jin, et al.
Publicado: (2023)

Prognostic Value of N6-Methyladenosine-Related lncRNAs in Early-Stage Colorectal Cancer: Association With Immune Cell Infiltration and Chemotherapeutic Drug Sensitivity
por: Xiong, Zhizhong, et al.
Publicado: (2021)

Clinical Eosinophil-Associated Genes can Serve as a Reliable Predictor of Bladder Urothelial Cancer
por: Xu, Chaojie, et al.
Publicado: (2022)

Malate-Aspartate Shuttle Plays an Important Role in LPS-Induced Neuroinflammation of Mice Due to its Effect on STAT3 Phosphorylation
por: Zhou, Cuiyan, et al.
Publicado: (2021)

The role of IGF2BP2, an m6A reader gene, in human metabolic diseases and cancers
por: Wang, Jinyan, et al.
Publicado: (2021)

Pan-Cancer Prognostic, Immunity, Stemness, and Anticancer Drug Sensitivity Characterization of N6-Methyladenosine RNA Modification Regulators in Human Cancers
por: Li, Rui, et al.
Publicado: (2021)

Validated Impacts of N6-Methyladenosine Methylated mRNAs on Apoptosis and Angiogenesis in Myocardial Infarction Based on MeRIP-Seq Analysis
por: Zhang, Yingjie, et al.
Publicado: (2022)

Regulation of Carbohydrate-Responsive Metabolic Genes by Histone Acetylation and the Acetylated Histone Reader BRD4 in the Gene Body Region
por: Mochizuki, Kazuki, et al.
Publicado: (2021)

A cutting-edge immunomodulatory interlinkage between HOTAIR and MALAT1 in tumor-associated macrophages in breast cancer: A personalized immunotherapeutic approach
por: Amer, Hoda T., et al.
Publicado: (2022)

N6-Methyladenosine RNA Methylation Regulator-Related Alternative Splicing (AS) Gene Signature Predicts Non–Small Cell Lung Cancer Prognosis
por: Zhao, Zhenyu, et al.
Publicado: (2021)

Identification and Validation of the N6-Methyladenosine RNA Methylation Regulator YTHDF1 as a Novel Prognostic Marker and Potential Target for Hepatocellular Carcinoma
por: Bian, Saiyan, et al.
Publicado: (2020)

FLCN Regulates HIF2α Nuclear Import and Proliferation of Clear Cell Renal Cell Carcinoma
por: Zhao, Xuyang, et al.
Publicado: (2020)

FCGR1A Serves as a Novel Biomarker and Correlates With Immune Infiltration in Four Cancer Types
por: Xu, Ji-li, et al.
Publicado: (2020)

Identification of the function and mechanism of m6A reader IGF2BP2 in Alzheimer’s disease
por: Deng, Yanyao, et al.
Publicado: (2021)

Targeting potential receptor molecules in non-small cell lung cancer (NSCLC) using in silico approaches
por: Kirubhanand, C., et al.
Publicado: (2023)

Dynamically Accumulating Homologous Recombination Deficiency Score Served as an Important Prognosis Factor in High-Grade Serous Ovarian Cancer
por: Su, Rongjia, et al.
Publicado: (2021)

An oncopeptide regulates m(6)A recognition by the m(6)A reader IGF2BP1 and tumorigenesis
por: Zhu, Song, et al.
Publicado: (2020)

N6-Methyladenosine Methyltransferase METTL3 Promotes Angiogenesis and Atherosclerosis by Upregulating the JAK2/STAT3 Pathway via m6A Reader IGF2BP1
por: Dong, Guo, et al.
Publicado: (2021)

PRR11 promotes cell proliferation by regulating PTTG1 through interacting with E2F1 transcription factor in pan-cancer
por: Zhang, Haibo, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_bojriltponmq394bt573ae5g5v