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A 3D Platform to Investigate Dynamic Cell-to-Cell Interactions Between Tumor Cells and Mesenchymal Progenitors

We here investigated the dynamic cell-to-cell interactions between tumor and mesenchymal stromal/stem cells (MSCs) by the novel VITVO(Ⓡ) 3D bioreactor that was customized to develop in vivo-like metastatic nodules of Ewing’s sarcoma (ES). MSCs are known to contribute to tumor microenvironment as can...

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Detalles Bibliográficos
Autores principales: Golinelli, Giulia, Talami, Rebecca, Frabetti, Stella, Candini, Olivia, Grisendi, Giulia, Spano, Carlotta, Chiavelli, Chiara, Arnaud, Gaëlle F., Mari, Giorgio, Dominici, Massimo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8802911/
https://www.ncbi.nlm.nih.gov/pubmed/35111750
http://dx.doi.org/10.3389/fcell.2021.767253