Cargando…

Angiotensin II receptor 1 controls profibrotic Wnt/β-catenin signalling in experimental autoimmune myocarditis

AIMS: Angiotensin (Ang) II signalling has been suggested to promote cardiac fibrosis in inflammatory heart diseases; however, the underlying mechanisms remain obscure. Using Agtr1a(-/-) mice with genetic deletion of angiotensin receptor type 1 (ATR1) and the experimental autoimmune myocarditis (EAM)...

Descripción completa

Detalles Bibliográficos
Autores principales: Czepiel, Marcin, Diviani, Dario, Jaźwa-Kusior, Agnieszka, Tkacz, Karolina, Rolski, Filip, Smolenski, Ryszard T, Siedlar, Maciej, Eriksson, Urs, Kania, Gabriela, Błyszczuk, Przemysław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803091/
https://www.ncbi.nlm.nih.gov/pubmed/33576779
http://dx.doi.org/10.1093/cvr/cvab039