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CD4+ T cells in classical Hodgkin lymphoma express exhaustion associated transcription factors TOX and TOX2: Characterizing CD4+ T cells in Hodgkin lymphoma

In classical Hodgkin lymphoma (cHL), the highly abundant CD4+ T cells in the vicinity of tumor cells are considered essential for tumor cell survival, but are ill-defined. Although they are activated, they consistently lack expression of activation marker CD26. In this study, we compared sorted CD4+...

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Detalles Bibliográficos
Autores principales: Veldman, Johanna, Rodrigues Plaça, Jessica, Chong, Lauren, Terpstra, Miente Martijn, Mastik, Mirjam, van Kempen, Léon C., Kok, Klaas, Aoki, Tomohiro, Steidl, Christian, van den Berg, Anke, Visser, Lydia, Diepstra, Arjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803106/
https://www.ncbi.nlm.nih.gov/pubmed/35111387
http://dx.doi.org/10.1080/2162402X.2022.2033433