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HRSV prefusion-F protein with Adju-Phos adjuvant induces long-lasting Th2-biased immunity in mice

The development of human respiratory syncytial virus (hRSV) vaccine has been hampered by the risk of enhanced respiratory disease (ERD) which was induced by highly skewed toward Th2 immune response. In our previous study, we expressed the recombinant pre-F protein using Escherichia coli BL21, called...

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Detalles Bibliográficos
Autores principales: Li, Hai, Ren, Hu, Zhou, Yangzi, Zhang, Yan, Cao, Lei, Xu, Wenbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803181/
https://www.ncbi.nlm.nih.gov/pubmed/35100303
http://dx.doi.org/10.1371/journal.pone.0262231