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HRSV prefusion-F protein with Adju-Phos adjuvant induces long-lasting Th2-biased immunity in mice
The development of human respiratory syncytial virus (hRSV) vaccine has been hampered by the risk of enhanced respiratory disease (ERD) which was induced by highly skewed toward Th2 immune response. In our previous study, we expressed the recombinant pre-F protein using Escherichia coli BL21, called...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803181/ https://www.ncbi.nlm.nih.gov/pubmed/35100303 http://dx.doi.org/10.1371/journal.pone.0262231 |