A high-dose inoculum size results in persistent viral infection and arthritis in mice infected with chikungunya virus

Chikungunya virus (CHIKV) is an emerging mosquito-transmitted alphavirus that leads to acute fever and chronic debilitating polyarthralgia. To date, the mechanism underlying chronic recurrent arthralgia is unknown. In the present study, newborn wild-type C57BL/6 mice were infected with CHIKV, and th...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Yan, Hu, Li, Xian, Zhou, Dihan, Zhong, Maohua, Yang, Jingyi, Zhao, Bali, Fan, Xuxu, Fan, Jun, Shu, Jiayi, Lu, Mengji, Jin, Xia, Zhang, Ejuan, Yan, Huimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803182/
https://www.ncbi.nlm.nih.gov/pubmed/35100271
http://dx.doi.org/10.1371/journal.pntd.0010149

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803182/
https://www.ncbi.nlm.nih.gov/pubmed/35100271
http://dx.doi.org/10.1371/journal.pntd.0010149

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