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Xbp1 and Brachyury establish an evolutionarily conserved subcircuit of the notochord gene regulatory network

Gene regulatory networks coordinate the formation of organs and structures that compose the evolving body plans of different organisms. We are using a simple chordate model, the Ciona embryo, to investigate the essential gene regulatory network that orchestrates morphogenesis of the notochord, a str...

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Detalles Bibliográficos
Autores principales: Wu, Yushi, Devotta, Arun, José-Edwards, Diana S, Kugler, Jamie E, Negrón-Piñeiro, Lenny J, Braslavskaya, Karina, Addy, Jermyn, Saint-Jeannet, Jean-Pierre, Di Gregorio, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803312/
https://www.ncbi.nlm.nih.gov/pubmed/35049502
http://dx.doi.org/10.7554/eLife.73992