A model of preferential pairing between epithelial and dendritic cells in thymic antigen transfer

Medullary thymic epithelial cells (mTECs), which produce and present self-antigens, are essential for the establishment of central tolerance. Since mTEC numbers are limited, their function is complemented by thymic dendritic cells (DCs), which transfer mTEC-produced self-antigens via cooperative ant...

Descripción completa

Detalles Bibliográficos
Autores principales: Vobořil, Matouš, Březina, Jiří, Brabec, Tomáš, Dobeš, Jan, Ballek, Ondřej, Dobešová, Martina, Manning, Jasper, Blumberg, Richard S, Filipp, Dominik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803313/
https://www.ncbi.nlm.nih.gov/pubmed/35099391
http://dx.doi.org/10.7554/eLife.71578