Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model

Studies using the nonhuman primate model of Mycobacterium tuberculosis/simian immunodeficiency virus coinfection have revealed protective CD4(+) T cell–independent immune responses that suppress latent tuberculosis infection (LTBI) reactivation. In particular, chronic immune activation rather than t...

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Detalles Bibliográficos
Autores principales: Sharan, Riti, Ganatra, Shashank R., Bucsan, Allison N., Cole, Journey, Singh, Dhiraj K., Alvarez, Xavier, Gough, Maya, Alvarez, Cynthia, Blakley, Alyssa, Ferdin, Justin, Thippeshappa, Rajesh, Singh, Bindu, Escobedo, Ruby, Shivanna, Vinay, Dick, Edward J., Hall-Ursone, Shannan, Khader, Shabaana A., Mehra, Smriti, Rengarajan, Jyothi, Kaushal, Deepak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803324/
https://www.ncbi.nlm.nih.gov/pubmed/34855621
http://dx.doi.org/10.1172/JCI153090

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803324/
https://www.ncbi.nlm.nih.gov/pubmed/34855621
http://dx.doi.org/10.1172/JCI153090

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