Cargando…

Antiretroviral therapy timing impacts latent tuberculosis infection reactivation in a Mycobacterium tuberculosis/SIV coinfection model

Studies using the nonhuman primate model of Mycobacterium tuberculosis/simian immunodeficiency virus coinfection have revealed protective CD4(+) T cell–independent immune responses that suppress latent tuberculosis infection (LTBI) reactivation. In particular, chronic immune activation rather than t...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sharan, Riti, Ganatra, Shashank R., Bucsan, Allison N., Cole, Journey, Singh, Dhiraj K., Alvarez, Xavier, Gough, Maya, Alvarez, Cynthia, Blakley, Alyssa, Ferdin, Justin, Thippeshappa, Rajesh, Singh, Bindu, Escobedo, Ruby, Shivanna, Vinay, Dick, Edward J., Hall-Ursone, Shannan, Khader, Shabaana A., Mehra, Smriti, Rengarajan, Jyothi, Kaushal, Deepak
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Clinical Investigation 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803324/ https://www.ncbi.nlm.nih.gov/pubmed/34855621 http://dx.doi.org/10.1172/JCI153090

Ejemplares similares

Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs
por: Sharan, Riti, et al.
Publicado: (2022)

Inhibition of indoleamine dioxygenase leads to better control of tuberculosis adjunctive to chemotherapy
por: Singh, Bindu, et al.
Publicado: (2023)

The current state of animal models and genomic approaches towards identifying and validating molecular determinants of Mycobacterium tuberculosis infection and tuberculosis disease
por: Bucsan, Allison N, et al.
Publicado: (2019)

Characterizing Early T Cell Responses in Nonhuman Primate Model of Tuberculosis
por: Sharan, Riti, et al.
Publicado: (2021)

System-wide identification of myeloid markers of TB disease and HIV-induced reactivation in the macaque model of Mtb infection and Mtb/SIV co-infection
por: Gough, Maya, et al.
Publicado: (2022)

Myeloid-Derived Suppressor Cells Mediate T Cell Dysfunction in Nonhuman Primate TB Granulomas
por: Singh, Bindu, et al.
Publicado: (2021)

Peripheral Blood Markers Correlate with the Progression of Active Tuberculosis Relative to Latent Control of Mycobacterium tuberculosis Infection in Macaques
por: Gough, Maya, et al.
Publicado: (2022)

In vivo inhibition of tryptophan catabolism reorganizes the tuberculoma and augments immune-mediated control of Mycobacterium tuberculosis
por: Gautam, Uma S., et al.
Publicado: (2018)

Myeloid cell interferon responses correlate with clearance of SARS-CoV-2
por: Singh, Dhiraj, et al.
Publicado: (2021)

Response to Hypoxia and the Ensuing Dysregulation of Inflammation Impacts Mycobacterium tuberculosis Pathogenicity
por: Bucşan, Allison N., et al.
Publicado: (2022)

Myeloid cell interferon responses correlate with clearance of SARS-CoV-2
por: Singh, Dhiraj K., et al.
Publicado: (2022)

Mucosal vaccination with attenuated Mycobacterium tuberculosis induces strong central memory responses and protects against tuberculosis
por: Kaushal, Deepak, et al.
Publicado: (2015)

HIV-1 and SIV Infection Are Associated with Early Loss of Lung Interstitial CD4+ T Cells and Dissemination of Pulmonary Tuberculosis
por: Corleis, Björn, et al.
Publicado: (2019)

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells
por: Sia, Jonathan Kevin, et al.
Publicado: (2015)

LAG-3 potentiates the survival of Mycobacterium tuberculosis in host phagocytes by modulating mitochondrial signaling in an in-vitro granuloma model
por: Phillips, Bonnie L., et al.
Publicado: (2017)

Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
por: Singh, Dhiraj Kumar, et al.
Publicado: (2020)

Author Correction: Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets
por: Singh, Dhiraj Kumar, et al.
Publicado: (2021)

Vaccination with intravenous BCG protects macaques with pre-existing SIV infection from tuberculosis
por: Larson, Erica C., et al.
Publicado: (2023)

Role of TNF in the Altered Interaction of Dormant Mycobacterium tuberculosis with Host Macrophages
por: Gautam, Uma S., et al.
Publicado: (2014)

SIV Evolutionary Dynamics in Cynomolgus Macaques during SIV-Mycobacterium tuberculosis Co-Infection
por: Tisthammer, Kaho H., et al.
Publicado: (2021)

High Frequencies of Caspase-3 Expressing Mycobacterium tuberculosis-Specific CD4(+) T Cells Are Associated With Active Tuberculosis
por: Adekambi, Toidi, et al.
Publicado: (2018)

Faithful Experimental Models of Human Mycobacterium Tuberculosis Infection
por: Kaushal, Deepak, et al.
Publicado: (2012)

SIV and Mycobacterium tuberculosis synergy within the granuloma accelerates the reactivation pattern of latent tuberculosis
por: Diedrich, Collin R., et al.
Publicado: (2020)

Transcriptional Reprogramming in Nonhuman Primate (Rhesus Macaque) Tuberculosis Granulomas
por: Mehra, Smriti, et al.
Publicado: (2010)

Distinct Effector Memory CD4(+) T Cell Signatures in Latent Mycobacterium tuberculosis Infection, BCG Vaccination and Clinically Resolved Tuberculosis
por: Adekambi, Toidi, et al.
Publicado: (2012)

Mycobacterium tuberculosis sensor kinase DosS modulates the autophagosome in a DosR-independent manner
por: Gautam, Uma S., et al.
Publicado: (2019)

SIV Infection Facilitates Mycobacterium tuberculosis Infection of Rhesus Macaques
por: Guo, Ming, et al.
Publicado: (2017)

Immune Responses in Lung Granulomas during Mtb/HIV Co-Infection: Implications for Pathogenesis and Therapy
por: Kaushal, Deepak, et al.
Publicado: (2023)

Transcriptional Response of Mycobacterium tuberculosis to Cigarette Smoke Condensate
por: Willemse, Danicke, et al.
Publicado: (2021)

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection
por: Rosa, Bruce A., et al.
Publicado: (2020)

IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection
por: Rosa, Bruce A., et al.
Publicado: (2021)

A recombinant attenuated Mycobacterium tuberculosis-SIV combination vaccine is safe and immunogenic in immunocompromised, SIV-infected infant macaques
por: Jensen, K, et al.
Publicado: (2012)

Abnormal Tryptophan Metabolism in HIV and Mycobacterium tuberculosis Infection
por: Wang, Xiaolei, et al.
Publicado: (2021)

Engaging the CD40-CD40L pathway augments T-helper cell responses and improves control of Mycobacterium tuberculosis infection
por: Sia, Jonathan Kevin, et al.
Publicado: (2017)

Advancing Adjuvants for Mycobacterium tuberculosis Therapeutics
por: Enriquez, Ana B., et al.
Publicado: (2021)

sncRNA-1 Is a Small Noncoding RNA Produced by Mycobacterium tuberculosis in Infected Cells That Positively Regulates Genes Coupled to Oleic Acid Biosynthesis
por: Coskun, Fatma S., et al.
Publicado: (2020)

In-Vivo Gene Signatures of Mycobacterium tuberculosis in C3HeB/FeJ Mice
por: Gautam, Uma Shankar, et al.
Publicado: (2015)

A Mycobacterium tuberculosis Sigma Factor Network Responds to Cell-Envelope Damage by the Promising Anti-Mycobacterial Thioridazine
por: Dutta, Noton K., et al.
Publicado: (2010)

Host Immunity to Mycobacterium tuberculosis Infection Is Similar in Simian Immunodeficiency Virus (SIV)-Infected, Antiretroviral Therapy-Treated and SIV-Naïve Juvenile Macaques
por: Larson, Erica C., et al.
Publicado: (2023)

Antibody glycosylation correlates with disease progression in SIV‐ Mycobacterium tuberculosis coinfected cynomolgus macaques
por: Haycroft, Ebene R, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_9qffii43mfo5e35o3dj13c65ul