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ALK1 signaling is required for the homeostasis of Kupffer cells and prevention of bacterial infection

Macrophages are highly heterogeneous immune cells that fulfill tissue-specific functions. Tissue-derived signals play a critical role in determining macrophage heterogeneity. However, these signals remain largely unknown. The BMP receptor activin receptor–like kinase 1 (ALK1) is well known for its r...

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Detalles Bibliográficos
Autores principales: Zhao, Dianyuan, Yang, Fengjiao, Wang, Yang, Li, Site, Li, Yang, Hou, Fei, Yang, Wenting, Liu, Di, Tao, Yuandong, Li, Qian, Wang, Jing, He, Fuchu, Tang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803331/
https://www.ncbi.nlm.nih.gov/pubmed/34874921
http://dx.doi.org/10.1172/JCI150489