Učitavanje…
Congenital deficiency reveals critical role of ISG15 in skin homeostasis
Ulcerating skin lesions are manifestations of human ISG15 deficiency, a type I interferonopathy. However, chronic inflammation may not be their exclusive cause. We describe two siblings with recurrent skin ulcers that healed with scar formation upon corticosteroid treatment. Both had a homozygous no...
Glavni autori: | , , , , , , , , , , , , , , , , , , , , |
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Format: | Online Članak Tekst |
Jezik: | English |
Izdano: |
American Society for Clinical Investigation
2022
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Teme: | |
Online pristup: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803340/ https://www.ncbi.nlm.nih.gov/pubmed/34847081 http://dx.doi.org/10.1172/JCI141573 |