β Cell function and plasma insulin clearance in people with obesity and different glycemic status

BACKGROUND: It is unclear how excess adiposity and insulin resistance affect β cell function, insulin secretion, and insulin clearance in people with obesity. METHODS: We used a hyperinsulinemic-euglycemic clamp procedure and a modified oral glucose tolerance test to evaluate the interrelationships...

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Detalles Bibliográficos
Autores principales: Mittendorfer, Bettina, Patterson, Bruce W., Smith, Gordon I., Yoshino, Mihoko, Klein, Samuel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Clinical Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803344/
https://www.ncbi.nlm.nih.gov/pubmed/34905513
http://dx.doi.org/10.1172/JCI154068

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803344/
https://www.ncbi.nlm.nih.gov/pubmed/34905513
http://dx.doi.org/10.1172/JCI154068

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