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The Natural Compound Dehydrocrenatidine Attenuates Nicotine-Induced Stemness and Epithelial-Mesenchymal Transition in Hepatocellular Carcinoma by Regulating a7nAChR-Jak2 Signaling Pathways

BACKGROUND: Exposure to nicotine has been observed associated with tumor progression, metastasis, and therapy resistance of many cancers. Hepatocellular carcinoma (HCC) is one major cancer related to the liver and the most difficult to treat malignancies worldwide. The underlying mechanism of nicoti...

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Detalles Bibliográficos
Autores principales: Li, Ching-Li, Wang, Chien-Che, Pai, Hsin-Te, Tu, Stan-Ley, Hou, Pin-Yuan, Huang, Chien-Yu, Huang, Ming-Te, Chang, Yu-Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803439/
https://www.ncbi.nlm.nih.gov/pubmed/35111269
http://dx.doi.org/10.1155/2022/8316335