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Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study

Aim: The Dietary Approaches to Stop Hypertension (DASH) diet is recommended for lowering blood pressure (BP). Our previous single-arm trial revealed that the Japanese cuisine-based DASH (J-DASH) diet (supplying NaCl 8.0 g per day) reduced BP and improved cardiometabolic biomarkers. The present study...

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Autores principales: Umemoto, Seiji, Onaka, Uran, Kawano, Reo, Kawamura, Atsuko, Motoi, Sayaka, Honda, Naoki, Kanazashi, Hiroki, Mitarai, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japan Atherosclerosis Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803568/
https://www.ncbi.nlm.nih.gov/pubmed/33298663
http://dx.doi.org/10.5551/jat.57802
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author Umemoto, Seiji
Onaka, Uran
Kawano, Reo
Kawamura, Atsuko
Motoi, Sayaka
Honda, Naoki
Kanazashi, Hiroki
Mitarai, Makoto
author_facet Umemoto, Seiji
Onaka, Uran
Kawano, Reo
Kawamura, Atsuko
Motoi, Sayaka
Honda, Naoki
Kanazashi, Hiroki
Mitarai, Makoto
author_sort Umemoto, Seiji
collection PubMed
description Aim: The Dietary Approaches to Stop Hypertension (DASH) diet is recommended for lowering blood pressure (BP). Our previous single-arm trial revealed that the Japanese cuisine-based DASH (J-DASH) diet (supplying NaCl 8.0 g per day) reduced BP and improved cardiometabolic biomarkers. The present study’s primary objective was to test the feasibility of the J-DASH diet based on its effects on the BP and BP variability of subjects with untreated high-normal BP or stage 1 hypertension. Methods: The 6-month study period was held from December 2015 to August 2016. The participants were recruited through advertisements in local newspapers and our website and from among randomized participants at Yamaguchi University Hospital. The 2-month treatments included the following: the J-DASH-1 diet 1×/day or the J-DASH-2 diet providing a fish hamburger-patty 2×/day (5 days/week respectively). The control group consumed their usual diets. For the subsequent 4 months, all participants consumed their usual diets. The main outcome measure was the feasibility of the J-DASH diet. We also collected the data of clinic BP and home BP (by automatic BP monitor), cardiometabolic biomarkers, and lifestyle and psychosocial parameters during the intervention phase. We examined behavior changes throughout the study period, and the diets’ safety. Results: Fifty-one participants were recruited; following screening, 48 met the inclusion criteria and were randomized by central allocation. Eight participants were eliminated based on exclusion criteria, and the 40 participants were randomly allocated to the J-DASH 1 and J-DASH 2 groups ( n =13 each) and the usual-diet group ( n =14). The participants’ mean age was 50 years, and 44% were women. The three groups’ clinic BP values were not significantly different, but the home BP values were lower in the J-DASH 1 group and lowest in the J-DASH 2 group compared to the usual-diet group and differed significantly among the three groups throughout the study period ( p <0.0001). The home BP variability was significantly lower in the J-DASH groups compared to the usual-diet group throughout the study period ( p <0.01). The other indices including fish oil showed little differences among the groups throughout the study period. Conclusions: The J-DASH diet was feasible to improve home BP and stabilize its variability, and it did so more effectively than the participants’ usual diets.
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spelling pubmed-88035682022-02-15 Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study Umemoto, Seiji Onaka, Uran Kawano, Reo Kawamura, Atsuko Motoi, Sayaka Honda, Naoki Kanazashi, Hiroki Mitarai, Makoto J Atheroscler Thromb Original Article Aim: The Dietary Approaches to Stop Hypertension (DASH) diet is recommended for lowering blood pressure (BP). Our previous single-arm trial revealed that the Japanese cuisine-based DASH (J-DASH) diet (supplying NaCl 8.0 g per day) reduced BP and improved cardiometabolic biomarkers. The present study’s primary objective was to test the feasibility of the J-DASH diet based on its effects on the BP and BP variability of subjects with untreated high-normal BP or stage 1 hypertension. Methods: The 6-month study period was held from December 2015 to August 2016. The participants were recruited through advertisements in local newspapers and our website and from among randomized participants at Yamaguchi University Hospital. The 2-month treatments included the following: the J-DASH-1 diet 1×/day or the J-DASH-2 diet providing a fish hamburger-patty 2×/day (5 days/week respectively). The control group consumed their usual diets. For the subsequent 4 months, all participants consumed their usual diets. The main outcome measure was the feasibility of the J-DASH diet. We also collected the data of clinic BP and home BP (by automatic BP monitor), cardiometabolic biomarkers, and lifestyle and psychosocial parameters during the intervention phase. We examined behavior changes throughout the study period, and the diets’ safety. Results: Fifty-one participants were recruited; following screening, 48 met the inclusion criteria and were randomized by central allocation. Eight participants were eliminated based on exclusion criteria, and the 40 participants were randomly allocated to the J-DASH 1 and J-DASH 2 groups ( n =13 each) and the usual-diet group ( n =14). The participants’ mean age was 50 years, and 44% were women. The three groups’ clinic BP values were not significantly different, but the home BP values were lower in the J-DASH 1 group and lowest in the J-DASH 2 group compared to the usual-diet group and differed significantly among the three groups throughout the study period ( p <0.0001). The home BP variability was significantly lower in the J-DASH groups compared to the usual-diet group throughout the study period ( p <0.01). The other indices including fish oil showed little differences among the groups throughout the study period. Conclusions: The J-DASH diet was feasible to improve home BP and stabilize its variability, and it did so more effectively than the participants’ usual diets. Japan Atherosclerosis Society 2022-02-01 2020-12-09 /pmc/articles/PMC8803568/ /pubmed/33298663 http://dx.doi.org/10.5551/jat.57802 Text en 2022 Japan Atherosclerosis Society https://creativecommons.org/licenses/by-nc-sa/4.0/This article is distributed under the terms of the latest version of CC BY-NC-SA defined by the Creative Commons Attribution License.http://creativecommons.org/licenses/by-nc-sa/4.0/ (https://creativecommons.org/licenses/by-nc-sa/4.0/)
spellingShingle Original Article
Umemoto, Seiji
Onaka, Uran
Kawano, Reo
Kawamura, Atsuko
Motoi, Sayaka
Honda, Naoki
Kanazashi, Hiroki
Mitarai, Makoto
Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title_full Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title_fullStr Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title_full_unstemmed Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title_short Effects of a Japanese Cuisine-Based Antihypertensive Diet and Fish Oil on Blood Pressure and Its Variability in Participants with Untreated Normal High Blood Pressure or Stage I Hypertension: A Feasibility Randomized Controlled Study
title_sort effects of a japanese cuisine-based antihypertensive diet and fish oil on blood pressure and its variability in participants with untreated normal high blood pressure or stage i hypertension: a feasibility randomized controlled study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803568/
https://www.ncbi.nlm.nih.gov/pubmed/33298663
http://dx.doi.org/10.5551/jat.57802
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