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Differential regulation of STP, LTP and LTD by structurally diverse NMDA receptor subunit-specific positive allosteric modulators

Different types of memory are thought to rely on different types of synaptic plasticity, many of which depend on the activation of the N-Methyl-D Aspartate (NMDA) subtype of glutamate receptors. Accordingly, there is considerable interest in the possibility of using positive allosteric modulators (P...

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Detalles Bibliográficos
Autores principales: France, G., Volianskis, R., Ingram, R., Bannister, N., Rothärmel, R., Irvine, M.W., Fang, G., Burnell, E.S., Sapkota, K., Costa, B.M., Chopra, D.A., Dravid, S.M., Michael-Titus, A.T., Monaghan, D.T., Georgiou, J., Bortolotto, Z.A., Jane, D.E., Collingridge, G.L., Volianskis, A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pergamon Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803579/
https://www.ncbi.nlm.nih.gov/pubmed/34678377
http://dx.doi.org/10.1016/j.neuropharm.2021.108840