WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice

BACKGROUND: The T cell receptor (TCR) diversity is essential for effective T cell immunity. Previous studies showed that TCR diversity in Wiskott–Aldrich Syndrome (WAS) patients was severely impaired, especially in the memory T cell populations. Whether this defect was caused by intrinsic WASp defic...

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Wenyan, Jia, Yanjun, Wang, Yanping, Zhao, Qin, Yang, Lu, Zeng, Ting, Niu, Linlin, Dai, Rongxin, Li, Yanan, Zhao, Xiaodong, Wu, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803657/
https://www.ncbi.nlm.nih.gov/pubmed/35116029
http://dx.doi.org/10.3389/fimmu.2021.794795

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803657/
https://www.ncbi.nlm.nih.gov/pubmed/35116029
http://dx.doi.org/10.3389/fimmu.2021.794795

Ejemplares similares