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WASp Deficiency Selectively Affects the TCR Diversity of Different Memory T Cell Subsets in WAS Chimeric Mice

BACKGROUND: The T cell receptor (TCR) diversity is essential for effective T cell immunity. Previous studies showed that TCR diversity in Wiskott–Aldrich Syndrome (WAS) patients was severely impaired, especially in the memory T cell populations. Whether this defect was caused by intrinsic WASp defic...

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Detalles Bibliográficos
Autores principales:	Li, Wenyan, Jia, Yanjun, Wang, Yanping, Zhao, Qin, Yang, Lu, Zeng, Ting, Niu, Linlin, Dai, Rongxin, Li, Yanan, Zhao, Xiaodong, Wu, Junfeng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803657/ https://www.ncbi.nlm.nih.gov/pubmed/35116029 http://dx.doi.org/10.3389/fimmu.2021.794795

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