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Fibroblast activation protein targeted therapy using [(177)Lu]FAPI-46 compared with [(225)Ac]FAPI-46 in a pancreatic cancer model
PURPOSE: Fibroblast activation protein (FAP), which has high expression in cancer-associated fibroblasts of epithelial cancers, can be used as a theranostic target. Our previous study used (64)Cu and (225)Ac-labelled FAP inhibitors (FAPI-04) for a FAP-expressing pancreatic cancer xenograft imaging a...
Autores principales: | Liu, Yuwei, Watabe, Tadashi, Kaneda-Nakashima, Kazuko, Shirakami, Yoshifumi, Naka, Sadahiro, Ooe, Kazuhiro, Toyoshima, Atsushi, Nagata, Kojiro, Haberkorn, Uwe, Kratochwil, Clemens, Shinohara, Atsushi, Hatazawa, Jun, Giesel, Frederik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803706/ https://www.ncbi.nlm.nih.gov/pubmed/34537893 http://dx.doi.org/10.1007/s00259-021-05554-2 |
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