The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice

AIMS/HYPOTHESIS: Second-generation antipsychotic (SGA) drugs have been associated with the development of type 2 diabetes and the metabolic syndrome in patients with schizophrenia. In this study, we aimed to investigate the effects of two different SGA drugs, olanzapine and aripiprazole, on metaboli...

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Detalles Bibliográficos
Autores principales: Grajales, Diana, Vázquez, Patricia, Ruíz-Rosario, Mónica, Tudurí, Eva, Mirasierra, Mercedes, Ferreira, Vítor, Hitos, Ana B., Koller, Dora, Zubiaur, Pablo, Cigudosa, Juan C., Abad-Santos, Francisco, Vallejo, Mario, Quesada, Iván, Tirosh, Boaz, Leibowitz, Gil, Valverde, Ángela M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803721/
https://www.ncbi.nlm.nih.gov/pubmed/34932133
http://dx.doi.org/10.1007/s00125-021-05630-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803721/
https://www.ncbi.nlm.nih.gov/pubmed/34932133
http://dx.doi.org/10.1007/s00125-021-05630-0

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