Cargando…
The second-generation antipsychotic drug aripiprazole modulates the serotonergic system in pancreatic islets and induces beta cell dysfunction in female mice
AIMS/HYPOTHESIS: Second-generation antipsychotic (SGA) drugs have been associated with the development of type 2 diabetes and the metabolic syndrome in patients with schizophrenia. In this study, we aimed to investigate the effects of two different SGA drugs, olanzapine and aripiprazole, on metaboli...
Autores principales: | Grajales, Diana, Vázquez, Patricia, Ruíz-Rosario, Mónica, Tudurí, Eva, Mirasierra, Mercedes, Ferreira, Vítor, Hitos, Ana B., Koller, Dora, Zubiaur, Pablo, Cigudosa, Juan C., Abad-Santos, Francisco, Vallejo, Mario, Quesada, Iván, Tirosh, Boaz, Leibowitz, Gil, Valverde, Ángela M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803721/ https://www.ncbi.nlm.nih.gov/pubmed/34932133 http://dx.doi.org/10.1007/s00125-021-05630-0 |
Ejemplares similares
-
Influence of CYP2D6 Phenotypes on the Pharmacokinetics of Aripiprazole and Dehydro-Aripiprazole Using a Physiologically Based Pharmacokinetic Approach
por: Kneller, Lisa Alina, et al.
Publicado: (2021) -
Genetic Polymorphisms Associated With the Pharmacokinetics, Pharmacodynamics and Adverse Effects of Olanzapine, Aripiprazole and Risperidone
por: Soria-Chacartegui, Paula, et al.
Publicado: (2021) -
Second-Generation Antipsychotics and Dysregulation of Glucose Metabolism: Beyond Weight Gain
por: Grajales, Diana, et al.
Publicado: (2019) -
Metabolic Effects of Aripiprazole and Olanzapine Multiple-Dose Treatment in a Randomised Crossover Clinical Trial in Healthy Volunteers: Association with Pharmacogenetics
por: Koller, Dora, et al.
Publicado: (2020) -
Antipsychotic treatments for the elderly: efficacy and safety of aripiprazole
por: Kohen, Izchak, et al.
Publicado: (2010)