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Two experts and a newbie: [(18)F]PARPi vs [(18)F]FTT vs [(18)F]FPyPARP—a comparison of PARP imaging agents

PURPOSE: Imaging of PARP expression has emerged as valuable strategy for prediction of tumor malignancy. While [(18)F]PARPi and [(18)F]FTT are already in clinical translation, both suffer from mainly hepatobiliary clearance hampering their use for detection of abdominal lesions, e.g., liver metastas...

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Detalles Bibliográficos
Autores principales: Stotz, Sophie, Kinzler, Johannes, Nies, Anne T., Schwab, Matthias, Maurer, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803746/
https://www.ncbi.nlm.nih.gov/pubmed/34486071
http://dx.doi.org/10.1007/s00259-021-05436-7