CXCR4 expression in glioblastoma tissue and the potential for PET imaging and treatment with [(68)Ga]Ga-Pentixafor /[(177)Lu]Lu-Pentixather

PURPOSE: CXCR4 (over)expression is found in multiple human cancer types, while expression is low or absent in healthy tissue. In glioblastoma it is associated with a poor prognosis and more extensive infiltrative phenotype. CXCR4 can be targeted by the diagnostic PET agent [(68)Ga]Ga-Pentixafor and...

Descripción completa

Detalles Bibliográficos
Autores principales: Jacobs, Sarah M., Wesseling, Pieter, de Keizer, Bart, Tolboom, Nelleke, Ververs, F. F. Tessa, Krijger, Gerard C., Westerman, Bart A., Snijders, Tom J., Robe, Pierre A., van der Kolk, Anja G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803771/
https://www.ncbi.nlm.nih.gov/pubmed/33550492
http://dx.doi.org/10.1007/s00259-021-05196-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803771/
https://www.ncbi.nlm.nih.gov/pubmed/33550492
http://dx.doi.org/10.1007/s00259-021-05196-4

Ejemplares similares