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CXCR4 expression in glioblastoma tissue and the potential for PET imaging and treatment with [(68)Ga]Ga-Pentixafor /[(177)Lu]Lu-Pentixather
PURPOSE: CXCR4 (over)expression is found in multiple human cancer types, while expression is low or absent in healthy tissue. In glioblastoma it is associated with a poor prognosis and more extensive infiltrative phenotype. CXCR4 can be targeted by the diagnostic PET agent [(68)Ga]Ga-Pentixafor and...
Autores principales: | Jacobs, Sarah M., Wesseling, Pieter, de Keizer, Bart, Tolboom, Nelleke, Ververs, F. F. Tessa, Krijger, Gerard C., Westerman, Bart A., Snijders, Tom J., Robe, Pierre A., van der Kolk, Anja G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803771/ https://www.ncbi.nlm.nih.gov/pubmed/33550492 http://dx.doi.org/10.1007/s00259-021-05196-4 |
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