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MicroRNA-193b impairs muscle growth in mouse models of type 2 diabetes by targeting the PDK1/Akt signalling pathway

AIMS/HYPOTHESIS: Type 2 diabetes is associated with a reduction in skeletal muscle mass; however, how the progression of sarcopenia is induced and regulated remains largely unknown. We aimed to find out whether a specific microRNA (miR) may contribute to skeletal muscle atrophy in type 2 diabetes. M...

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Detalles Bibliográficos
Autores principales: Yang, Shu, Yang, Guangyan, Wu, Han, Kang, Lin, Xiang, Jiaqing, Zheng, Peilin, Qiu, Shanhu, Liang, Zhen, Lu, Yan, Jia, Lijing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803817/
https://www.ncbi.nlm.nih.gov/pubmed/34913989
http://dx.doi.org/10.1007/s00125-021-05616-y