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H84T BanLec has broad spectrum antiviral activity against human herpesviruses in cells, skin, and mice

H84T BanLec is a molecularly engineered lectin cloned from bananas with broad-spectrum antiviral activity against several RNA viruses. H84T BanLec dimers bind glycoproteins containing high-mannose N-glycans on the virion envelope, blocking attachment, entry, uncoating, and spread. It was unknown whe...

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Detalles Bibliográficos
Autores principales: Lloyd, M. G., Liu, D., Legendre, M., Markovitz, D. M., Moffat, J. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803833/
https://www.ncbi.nlm.nih.gov/pubmed/35102178
http://dx.doi.org/10.1038/s41598-022-05580-6