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H84T BanLec has broad spectrum antiviral activity against human herpesviruses in cells, skin, and mice
H84T BanLec is a molecularly engineered lectin cloned from bananas with broad-spectrum antiviral activity against several RNA viruses. H84T BanLec dimers bind glycoproteins containing high-mannose N-glycans on the virion envelope, blocking attachment, entry, uncoating, and spread. It was unknown whe...
Autores principales: | Lloyd, M. G., Liu, D., Legendre, M., Markovitz, D. M., Moffat, J. F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803833/ https://www.ncbi.nlm.nih.gov/pubmed/35102178 http://dx.doi.org/10.1038/s41598-022-05580-6 |
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