Modeling and measuring glucose diffusion and consumption by colorectal cancer spheroids in hanging drops using integrated biosensors

As 3D in vitro tissue models become more pervasive, their built-in nutrient, metabolite, compound, and waste gradients increase biological relevance at the cost of analysis simplicity. Investigating these gradients and the resulting metabolic heterogeneity requires invasive and time-consuming method...

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Detalles Bibliográficos
Autores principales: Rousset, Nassim, Sandoval, Rubén López, Modena, Mario Matteo, Hierlemann, Andreas, Misun, Patrick M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803859/
https://www.ncbi.nlm.nih.gov/pubmed/35136653
http://dx.doi.org/10.1038/s41378-021-00348-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803859/
https://www.ncbi.nlm.nih.gov/pubmed/35136653
http://dx.doi.org/10.1038/s41378-021-00348-w

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