Splicing is an alternate oncogenic pathway activation mechanism in glioma

High-grade diffuse glioma (HGG) is the leading cause of brain tumour death. While the genetic drivers of HGG have been well described, targeting these has thus far had little impact on survival suggesting other mechanisms are at play. Here we interrogate the alternative splicing landscape of pediatr...

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Detalles Bibliográficos
Autores principales: Siddaway, Robert, Milos, Scott, Vadivel, Arun Kumaran Anguraj, Dobson, Tara H. W., Swaminathan, Jyothishmathi, Ryall, Scott, Pajovic, Sanja, Patel, Palak G., Nazarian, Javad, Becher, Oren, Brudno, Michael, Ramani, Arun, Gopalakrishnan, Vidya, Hawkins, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803922/
https://www.ncbi.nlm.nih.gov/pubmed/35102191
http://dx.doi.org/10.1038/s41467-022-28253-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803922/
https://www.ncbi.nlm.nih.gov/pubmed/35102191
http://dx.doi.org/10.1038/s41467-022-28253-4

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