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Differential release of extracellular vesicle tRNA from oxidative stressed renal cells and ischemic kidneys

While urine-based liquid biopsy has expanded to the analyses of extracellular nucleic acids, the potential of transfer RNA (tRNA) encapsulated within extracellular vesicles has not been explored as a new class of urine biomarkers for kidney injury. Using rat kidney and mouse tubular cell injury mode...

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Detalles Bibliográficos
Autores principales: Lee, Hee Kyung, Lee, Byung Rho, Lee, Tae Jin, Lee, Chang Min, Li, Chenglong, O’Connor, Paul M., Dong, Zheng, Kwon, Sang-Ho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8803936/
https://www.ncbi.nlm.nih.gov/pubmed/35102218
http://dx.doi.org/10.1038/s41598-022-05648-3