Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration

To control sprouting angiogenesis, endothelial Notch signaling suppresses tip cell formation, migration, and proliferation while promoting barrier formation. Each of these responses may be regulated by distinct Notch-regulated effectors. Notch activity is highly dynamic in sprouting endothelial cell...

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Detalles Bibliográficos
Autores principales: Swaminathan, Bhairavi, Youn, Seock-Won, Naiche, L. A., Du, Jing, Villa, Stephanie R., Metz, Jordan B., Feng, Huijuan, Zhang, Chaolin, Kopan, Raphael, Sims, Peter A., Kitajewski, Jan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804000/
https://www.ncbi.nlm.nih.gov/pubmed/35102202
http://dx.doi.org/10.1038/s41598-022-05666-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804000/
https://www.ncbi.nlm.nih.gov/pubmed/35102202
http://dx.doi.org/10.1038/s41598-022-05666-1

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