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Endothelial Notch signaling directly regulates the small GTPase RND1 to facilitate Notch suppression of endothelial migration
To control sprouting angiogenesis, endothelial Notch signaling suppresses tip cell formation, migration, and proliferation while promoting barrier formation. Each of these responses may be regulated by distinct Notch-regulated effectors. Notch activity is highly dynamic in sprouting endothelial cell...
Autores principales: | Swaminathan, Bhairavi, Youn, Seock-Won, Naiche, L. A., Du, Jing, Villa, Stephanie R., Metz, Jordan B., Feng, Huijuan, Zhang, Chaolin, Kopan, Raphael, Sims, Peter A., Kitajewski, Jan K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804000/ https://www.ncbi.nlm.nih.gov/pubmed/35102202 http://dx.doi.org/10.1038/s41598-022-05666-1 |
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