N-Acylethanolamine Acid Amidase Inhibition Potentiates Morphine Analgesia and Delays the Development of Tolerance

Opioids are essential drugs for pain management, although long-term use is accompanied by tolerance, necessitating dose escalation, and dependence. Pharmacological treatments that enhance opioid analgesic effects and/or attenuate the development of tolerance (with a desirable opioid-sparing effect i...

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Detalles Bibliográficos
Autores principales: Congiu, Mauro, Micheli, Laura, Santoni, Michele, Sagheddu, Claudia, Muntoni, Anna Lisa, Makriyannis, Alexandros, Malamas, Michael S., Ghelardini, Carla, Di Cesare Mannelli, Lorenzo, Pistis, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804012/
https://www.ncbi.nlm.nih.gov/pubmed/34553321
http://dx.doi.org/10.1007/s13311-021-01116-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804012/
https://www.ncbi.nlm.nih.gov/pubmed/34553321
http://dx.doi.org/10.1007/s13311-021-01116-4

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