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Anti-Inflammatory and Pro-Autophagy Effects of the Cannabinoid Receptor CB2R: Possibility of Modulation in Type 1 Diabetes

Type 1 diabetes mellitus (T1DM) is an autoimmune disease resulting from loss of insulin-secreting β-cells in islets of Langerhans. The loss of β-cells is initiated when self-tolerance to β-cell-derived contents breaks down, which leads to T cell-mediated β-cell damage and, ultimately, β-cell apoptos...

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Detalles Bibliográficos
Autores principales: Liu, Qing-Rong, Aseer, Kanikkai Raja, Yao, Qin, Zhong, Xiaoming, Ghosh, Paritosh, O’Connell, Jennifer F., Egan, Josephine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804091/
https://www.ncbi.nlm.nih.gov/pubmed/35115945
http://dx.doi.org/10.3389/fphar.2021.809965