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E2F4-Based Gene Therapy Mitigates the Phenotype of the Alzheimer’s Disease Mouse Model 5xFAD

After decades of unfruitful work, no effective therapies are available for Alzheimer’s disease (AD), likely due to its complex etiology that requires a multifactorial therapeutic approach. We have recently shown using transgenic mice that E2 factor 4 (E2F4), a transcription factor that regulates cel...

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Detalles Bibliográficos
Autores principales: López-Sánchez, Noelia, Garrido-García, Alberto, Ramón-Landreau, Morgan, Cano-Daganzo, Vanesa, Frade, José M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804140/
https://www.ncbi.nlm.nih.gov/pubmed/34766258
http://dx.doi.org/10.1007/s13311-021-01151-1