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E2F4-Based Gene Therapy Mitigates the Phenotype of the Alzheimer’s Disease Mouse Model 5xFAD
After decades of unfruitful work, no effective therapies are available for Alzheimer’s disease (AD), likely due to its complex etiology that requires a multifactorial therapeutic approach. We have recently shown using transgenic mice that E2 factor 4 (E2F4), a transcription factor that regulates cel...
Autores principales: | López-Sánchez, Noelia, Garrido-García, Alberto, Ramón-Landreau, Morgan, Cano-Daganzo, Vanesa, Frade, José M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804140/ https://www.ncbi.nlm.nih.gov/pubmed/34766258 http://dx.doi.org/10.1007/s13311-021-01151-1 |
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