Effective use of sequence information to predict CRISPR-Cas9 off-target

The CRISPR/Cas9 gene-editing system is the third-generation gene-editing technology that has been widely used in biomedical applications. However, off-target effects occurring CRISPR/Cas9 system has been a challenging problem it faces in practical applications. Although many predictive models have b...

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Detalles Bibliográficos
Autores principales: Zhang, Zhong-Rui, Jiang, Zhen-Ran
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804193/
https://www.ncbi.nlm.nih.gov/pubmed/35140885
http://dx.doi.org/10.1016/j.csbj.2022.01.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804193/
https://www.ncbi.nlm.nih.gov/pubmed/35140885
http://dx.doi.org/10.1016/j.csbj.2022.01.006

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