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TRPV1-Mediated Microglial Autophagy Attenuates Alzheimer’s Disease-Associated Pathology and Cognitive Decline

Autophagy is a major regulator of the ageing process of the central nervous system and neurodegeneration. Autophagy dysfunction has been implicated in the pathogenesis of Alzheimer’s disease (AD). TRPV1 was reported to regulate autophagy to protect against foam cell formation and reduce the release...

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Detalles Bibliográficos
Autores principales: Wang, Chenfei, Huang, Wei, Lu, Jia, Chen, Hongzhuan, Yu, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804218/
https://www.ncbi.nlm.nih.gov/pubmed/35115924
http://dx.doi.org/10.3389/fphar.2021.763866