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Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation

The activation of hypoxia-inducible factor 1α (HIF-1α) signaling has promising implications for the treatment of bone diseases such as osteoporosis and skeletal fractures. However, the effects of manipulating HIF-1α pathway on bone micro-structure and remodeling should be fully studied before the cl...

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Detalles Bibliográficos
Autores principales: Chen, Kaizhe, Zhao, Jian, Qiu, Minglong, Zhang, Lianfang, Yang, Kai, Chang, Leilei, Jia, Peng, Qi, Jin, Deng, Lianfu, Li, Changwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804240/
https://www.ncbi.nlm.nih.gov/pubmed/35118061
http://dx.doi.org/10.3389/fcell.2021.721561