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Osteocytic HIF-1α Pathway Manipulates Bone Micro-structure and Remodeling via Regulating Osteocyte Terminal Differentiation
The activation of hypoxia-inducible factor 1α (HIF-1α) signaling has promising implications for the treatment of bone diseases such as osteoporosis and skeletal fractures. However, the effects of manipulating HIF-1α pathway on bone micro-structure and remodeling should be fully studied before the cl...
Autores principales: | Chen, Kaizhe, Zhao, Jian, Qiu, Minglong, Zhang, Lianfang, Yang, Kai, Chang, Leilei, Jia, Peng, Qi, Jin, Deng, Lianfu, Li, Changwei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804240/ https://www.ncbi.nlm.nih.gov/pubmed/35118061 http://dx.doi.org/10.3389/fcell.2021.721561 |
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