UBA6 and NDFIP1 regulate the degradation of ferroportin

Hepcidin regulates iron homeostasis by controlling the level of ferroportin, the only membrane channel that facilitates export of iron from within cells. Binding of hepcidin to ferroportin induces the ubiquitination of ferroportin at multiple lysine residues and subsequently causes the internalizati...

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Detalles Bibliográficos
Autores principales: Traeger, Lisa, Wiegand, Steffen B., Sauer, Andrew J., Corman, Benjamin H.P., Peneyra, Kathryn M., Wunderer, Florian, Fischbach, Anna, Bagchi, Aranya, Malhotra, Rajeev, Zapol, Warren M., Bloch, Donald B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804582/
https://www.ncbi.nlm.nih.gov/pubmed/34320783
http://dx.doi.org/10.3324/haematol.2021.278530

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804582/
https://www.ncbi.nlm.nih.gov/pubmed/34320783
http://dx.doi.org/10.3324/haematol.2021.278530

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