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The HIF‐1α pathway plays a critical role in salivary gland development in ex vivo organ cultures

The transcription factor, hypoxia‐inducible factor‐1α (HIF‐1α), has previously been shown to upregulate the expression of hypoxia‐related genes, including erythropoietin (EPO). However, the role of hypoxia‐inducible factor‐1α in morphogenesis during salivary gland development is unclear. We investig...

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Detalles Bibliográficos
Autores principales: Kimura, Tomomasa, Sakai, Manabu, Gojo, Nao, Watanabe, Mikio, Uzawa, Narikazu, Sakai, Takayoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804608/
https://www.ncbi.nlm.nih.gov/pubmed/34904400
http://dx.doi.org/10.1002/2211-5463.13351