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Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56(bright)CD16(−) subset

BACKGROUND: Toll-like receptors (TLRs) are pattern-recognition sensors mainly expressed in innate immune cells that directly recognize conserved pathogen structures (pathogen-associated molecular patterns-PAMPs). Natural killer (NK) cells have been described to express different endosomal TLRs trigg...

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Detalles Bibliográficos
Autores principales: Veneziani, Irene, Alicata, Claudia, Pelosi, Andrea, Landolina, Nadine, Ricci, Biancamaria, D'Oria, Valentina, Fagotti, Anna, Scambia, Giovanni, Moretta, Lorenzo, Maggi, Enrico
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804697/
https://www.ncbi.nlm.nih.gov/pubmed/35091452
http://dx.doi.org/10.1136/jitc-2021-003385