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Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56(bright)CD16(−) subset
BACKGROUND: Toll-like receptors (TLRs) are pattern-recognition sensors mainly expressed in innate immune cells that directly recognize conserved pathogen structures (pathogen-associated molecular patterns-PAMPs). Natural killer (NK) cells have been described to express different endosomal TLRs trigg...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804697/ https://www.ncbi.nlm.nih.gov/pubmed/35091452 http://dx.doi.org/10.1136/jitc-2021-003385 |