Cargando…

Toll-like receptor 8 agonists improve NK-cell function primarily targeting CD56(bright)CD16(−) subset

BACKGROUND: Toll-like receptors (TLRs) are pattern-recognition sensors mainly expressed in innate immune cells that directly recognize conserved pathogen structures (pathogen-associated molecular patterns-PAMPs). Natural killer (NK) cells have been described to express different endosomal TLRs trigg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Veneziani, Irene, Alicata, Claudia, Pelosi, Andrea, Landolina, Nadine, Ricci, Biancamaria, D'Oria, Valentina, Fagotti, Anna, Scambia, Giovanni, Moretta, Lorenzo, Maggi, Enrico
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2022
Materias:	Basic Tumor Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804697/ https://www.ncbi.nlm.nih.gov/pubmed/35091452 http://dx.doi.org/10.1136/jitc-2021-003385

Ejemplares similares

IL-1R8 silencing improves the anti-tumor function of freshly isolated human NK cells
por: Landolina, Nadine, et al.
Publicado: (2022)

Correction: Toll-like reReceptor 8 agonists improve NK-cell function primarily targeting CD56(bright)CD16(−) subset
Publicado: (2022)

PILRα binds an unknown receptor expressed primarily on CD56(bright) and decidual-NK cells and activates NK cell functions
por: Ophir, Yael, et al.
Publicado: (2016)

The Latest Approach of Immunotherapy with Endosomal TLR Agonists Improving NK Cell Function: An Overview
por: Veneziani, Irene, et al.
Publicado: (2022)

Reduction of the CD16(−)CD56(bright) NK Cell Subset Precedes NK Cell Dysfunction in Prostate Cancer
por: Koo, Kyo Chul, et al.
Publicado: (2013)

NK cells CD56(bright) and CD56(dim) subset cytokine loss and exhaustion is associated with impaired survival in myeloma
por: Seymour, Frances, et al.
Publicado: (2022)

The Increased Ratio of Blood CD56(bright) NK to CD56(dim) NK Is a Distinguishing Feature of Primary Sjögren's Syndrome
por: Ming, Bingxia, et al.
Publicado: (2020)

Oncolytic virus treatment differentially affects the CD56(dim) and CD56(bright) NK cell subsets in vivo and regulates a spectrum of human NK cell activity
por: Wantoch, Michelle, et al.
Publicado: (2022)

How the Immune System Responds to Allergy Immunotherapy
por: Veneziani, Irene, et al.
Publicado: (2022)

Ageing is associated with a decline in peripheral blood CD56(bright )NK cells
por: Chidrawar, Shivani M, et al.
Publicado: (2006)

Circulating CD56(bright) NK cells inversely correlate with survival of melanoma patients
por: de Jonge, Kaat, et al.
Publicado: (2019)

Loss of CCR7 Expression on CD56(bright) NK Cells Is Associated with a CD56(dim)CD16(+) NK Cell-Like Phenotype and Correlates with HIV Viral Load
por: Hong, Henoch S., et al.
Publicado: (2012)

Regulation of Development of CD56(bright)CD11c(+) NK-like Cells with Helper Function by IL-18
por: Li, Wen, et al.
Publicado: (2013)

Single-cell profiling reveals periventricular CD56(bright) NK cell accumulation in multiple sclerosis
por: Rodríguez-Lorenzo, Sabela, et al.
Publicado: (2022)

The co-inhibitory receptor TIGIT regulates NK cell function and is upregulated in human intrahepatic CD56(bright) NK cells
por: Ziegler, Annerose E., et al.
Publicado: (2023)

Decidual CXCR4(+)CD56(bright)NK cells as a novel NK subset in maternal–foetal immune tolerance to alleviate early pregnancy failure
por: Tao, Yu, et al.
Publicado: (2021)

Ovarian Cancer-Associated Ascites Have High Proportions of Cytokine-Responsive CD56bright NK Cells
por: Tonetti, Cláudia Rodrigues, et al.
Publicado: (2021)

Distinct Signatures in the Receptor Repertoire Discriminate CD56bright and CD56dim Natural Killer Cells
por: Schwane, Vera, et al.
Publicado: (2020)

Redistribution and Activation of CD16brightCD56dim NK Cell Subset to Fight against Omicron Subvariant BA.2 after COVID-19 Vaccination
por: Peng, Huiyun, et al.
Publicado: (2023)

Staphylococcus aureus β-Hemolysin Up-Regulates the Expression of IFN-γ by Human CD56(bright) NK Cells
por: Guan, Zhangchun, et al.
Publicado: (2021)

Evaluation of CD56(dim) and CD56(bright) natural killer cells in peripheral blood of women with IVF failures
por: Mardanian, Farahnaz, et al.
Publicado: (2015)

A Subset of PD-1-Expressing CD56(bright) NK Cells Identifies Patients with Good Response to Immune Checkpoint Inhibitors in Lung Cancer
por: Gascón-Ruiz, Marta, et al.
Publicado: (2023)

Human Natural Killer Cell Maturation Defect Supports In Vivo CD56(bright) to CD56(dim) Lineage Development
por: Domaica, Carolina Inés, et al.
Publicado: (2012)

CD56(bright) natural killer cells preferentially kill proliferating CD4(+) T cells
por: Lee, Mercede, et al.
Publicado: (2023)

Human Hepatic CD56(bright) NK Cells Display a Tissue-Resident Transcriptional Profile and Enhanced Ability to Kill Allogenic CD8(+) T Cells
por: Jameson, Gráinne, et al.
Publicado: (2022)

CD56(dim)CD16(high) and CD56(bright)CD16(−) cell percentages associated with maximum knee extensor strength and incidence of death in elderly
por: Senpuku, Hidenobu, et al.
Publicado: (2016)

The phenotype of CD3–CD56(bright) and CD3–CD56(dim) natural killer cells in systemic lupus erythematosus patients and its relation to disease activity
por: Soelistyoningsih, Dwi, et al.
Publicado: (2022)

Increased CD56(bright) NK cells in HIV-HCV co-infection and HCV mono-infection are associated with distinctive alterations of their phenotype
por: Bhardwaj, Suvercha, et al.
Publicado: (2016)

Hobit expression by a subset of human liver-resident CD56(bright) Natural Killer cells
por: Lunemann, Sebastian, et al.
Publicado: (2017)

Alterations in the CD56(−) and CD56(+) T Cell Subsets during COVID-19
por: Vavilova, Julia D., et al.
Publicado: (2023)

The CXCR3(+)CD56Bright Phenotype Characterizes a Distinct NK Cell Subset with Anti-Fibrotic Potential That Shows Dys-Regulated Activity in Hepatitis C
por: Eisenhardt, Marianne, et al.
Publicado: (2012)

High number of CD56(bright) NK-cells and persistently low CD4(+) T-cells in a hemophiliac HIV/HCV co-infected patient without opportunistic infections
por: Fregni, Giulia, et al.
Publicado: (2013)

Enrichment of CD56(dim)KIR+CD57+ highly cytotoxic NK cells in tumor infiltrated lymph nodes of melanoma patients
por: Ali, Talib Hassan, et al.
Publicado: (2014)

KLRF1, a novel marker of CD56(bright) NK cells, predicts improved survival for patients with locally advanced bladder cancer
por: Mukherjee, Neelam, et al.
Publicado: (2022)

CD56(dim)CD16(dim) Natural Killer (NK) Cells: The Forgotten Population
por: Zimmer, Jacques
Publicado: (2020)

Human Circulating and Tissue-Resident CD56(bright) Natural Killer Cell Populations
por: Melsen, Janine E., et al.
Publicado: (2016)

Increased expression of TIGIT and KLRG1 correlates with impaired CD56(bright) NK cell immunity in HPV16-related cervical intraepithelial neoplasia
por: Nie, You, et al.
Publicado: (2022)

Cytotoxicity of CD56(bright) NK Cells towards Autologous Activated CD4(+) T Cells Is Mediated through NKG2D, LFA-1 and TRAIL and Dampened via CD94/NKG2A
por: Nielsen, Natasja, et al.
Publicado: (2012)

Expansion of CD56(dim)CD16(neg) NK Cell Subset and Increased Inhibitory KIRs in Hospitalized COVID-19 Patients
por: Casado, José L., et al.
Publicado: (2021)

Pediatric Tumors-Mediated Inhibitory Effect on NK Cells: The Case of Neuroblastoma and Wilms’ Tumors
por: Pelosi, Andrea, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_u8kljuivap1ced9038685tjdkd