A very long-acting IL-15: implications for the immunotherapy of cancer

BACKGROUND: Interleukin-15 (IL-15) is an important cytokine necessary for proliferation and maintenance of natural killer (NK) and CD8(+) T cells, and with great promise as an immuno-oncology therapeutic. However, IL-15 has a very short half-life and a single administration does not provide the sust...

Descripción completa

Detalles Bibliográficos
Autores principales: Hangasky, John A, Chen, Wei, Dubois, Sigrid P, Daenthanasanmak, Anusara, Müller, Jürgen R, Reid, Ralph, Waldmann, Thomas A, Santi, Daniel V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2022
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804710/
https://www.ncbi.nlm.nih.gov/pubmed/35101947
http://dx.doi.org/10.1136/jitc-2021-004104

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804710/
https://www.ncbi.nlm.nih.gov/pubmed/35101947
http://dx.doi.org/10.1136/jitc-2021-004104

Ejemplares similares