Cargando…

Oxidative stress protein Oxr1 promotes V‐ATPase holoenzyme disassembly in catalytic activity‐independent manner

The vacuolar ATPase (V‐ATPase) is a rotary motor proton pump that is regulated by an assembly equilibrium between active holoenzyme and autoinhibited V(1)‐ATPase and V(o) proton channel subcomplexes. Here, we report cryo‐EM structures of yeast V‐ATPase assembled in vitro from lipid nanodisc reconsti...

Descripción completa

Detalles Bibliográficos
Autores principales: Khan, Md. Murad, Lee, Seowon, Couoh‐Cardel, Sergio, Oot, Rebecca A, Kim, Hyunmin, Wilkens, Stephan, Roh, Soung‐Hun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8804929/
https://www.ncbi.nlm.nih.gov/pubmed/34918374
http://dx.doi.org/10.15252/embj.2021109360