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Low-Dose Exposure to Ganglioside-Mimicking Bacteria Tolerizes Human Macrophages to Guillain-Barré Syndrome-Associated Antigens

Early in life, commensal bacteria play a major role in immune development, helping to guide the host response toward harmful stimuli while tolerating harmless antigens to prevent autoimmunity. Guillain-Barré syndrome (GBS) is an autoimmune disease caused by errant immune attack of antibody-bound gan...

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Detalles Bibliográficos
Autores principales: Patry, Robert T., Essler, Lauren, Andresen, Silke, Quinn, Frederick D., Szymanski, Christine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805021/
https://www.ncbi.nlm.nih.gov/pubmed/35100875
http://dx.doi.org/10.1128/mbio.03852-21