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An Analysis of the Novel Fluorocycline TP-6076 Bound to Both the Ribosome and Multidrug Efflux Pump AdeJ from Acinetobacter baumannii

Antibiotic resistance among bacterial pathogens continues to pose a serious global health threat. Multidrug-resistant (MDR) strains of the Gram-negative organism Acinetobacter baumannii utilize a number of resistance determinants to evade current antibiotics. One of the major resistance mechanisms e...

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Detalles Bibliográficos
Autores principales: Morgan, Christopher E., Zhang, Zhemin, Bonomo, Robert A., Yu, Edward W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805024/
https://www.ncbi.nlm.nih.gov/pubmed/35100868
http://dx.doi.org/10.1128/mbio.03732-21