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Gasdermin D Inhibits Coronavirus Infection by Promoting the Noncanonical Secretion of Beta Interferon

Pyroptosis, a programmed cell death, functions as an innate immune effector mechanism and plays a crucial role against microbial invasion. Gasdermin D (GSDMD), as the main pyroptosis effector, mediates pyroptosis and promotes releasing proinflammatory molecules into the extracellular environment thr...

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Detalles Bibliográficos
Autores principales: Zhao, Liyuan, Li, Liang, Xue, Mei, Liu, Xiang, Jiang, Chengfan, Wang, Wenzhe, Tang, Lijie, Feng, Li, Liu, Pinghuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8805026/
https://www.ncbi.nlm.nih.gov/pubmed/35100869
http://dx.doi.org/10.1128/mbio.03600-21